$ cat ./records/gates-foundation-commits-75-million-to-target-malaria-crispr-gene-2005.txt
Gates Foundation Commits $75 Million to Target Malaria CRISPR Gene Drive Research Program
[RECORD.TXT] · cat --full
The Gates Foundation provided foundational and cumulative grant funding totalling $75 million to Target Malaria, a non-profit research consortium based at Imperial College London, to develop CRISPR-based gene drive technology for malaria mosquito control. Target Malaria installs a gene drive into Anopheles gambiae mosquitoes that renders females sterile, spreading the modification through wild populations faster than natural inheritance. The foundation's investment made Target Malaria the best-funded gene drive programme in the world.
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Related Accomplishments
January 2026
Gates-backed World Mosquito Program reaches 16 million people protected from dengue via Wolbachia method
The World Mosquito Program — backed in part by the Gates Foundation — announced in January 2026 that its Wolbachia-infected mosquito releases had reached over 16.1 million people across multiple countries, including Colombia, Indonesia, Brazil, Sri Lanka, Fiji, Vanuatu, and Vietnam. Wolbachia-carrying Aedes aegypti mosquitoes — which block dengue, Zika, chikungunya, and yellow fever transmission — had established self-sustaining populations in treated cities without requiring ongoing releases. Gold-standard randomised trials in Indonesia showed a 77% reduction in dengue incidence. The program represented one of the largest and most cost-effective vector control deployments in history.
2025
Gates-Funded Monoclonal Antibody Shows Early Promise as a Single-Shot Malaria Shield
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