Gates Foundation Commits $169 Million to Serum Institute for R21/Matrix-M Malaria Vaccine Manufacturing
The Gates Foundation committed $169 million to the Serum Institute of India to manufacture the R21/Matrix-M malaria vaccine developed by the University of Oxford with Novavax's adjuvant. R21/Matrix-M achieved 75 percent efficacy in Phase III trials across Burkina Faso, Mali, Kenya, and Tanzania — the highest efficacy ever reported for a malaria vaccine. The WHO recommended R21 in October 2023, expanding global malaria vaccine supply from 15 million to nearly 100 million doses annually.
Source: https://www.ox.ac.uk/news/2021-04-23-oxford-malaria-vaccine-results-published-lancet
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January 2026
Gates-backed World Mosquito Program reaches 16 million people protected from dengue via Wolbachia method
The World Mosquito Program — backed in part by the Gates Foundation — announced in January 2026 that its Wolbachia-infected mosquito releases had reached over 16.1 million people across multiple countries, including Colombia, Indonesia, Brazil, Sri Lanka, Fiji, Vanuatu, and Vietnam. Wolbachia-carrying Aedes aegypti mosquitoes — which block dengue, Zika, chikungunya, and yellow fever transmission — had established self-sustaining populations in treated cities without requiring ongoing releases. Gold-standard randomised trials in Indonesia showed a 77% reduction in dengue incidence. The program represented one of the largest and most cost-effective vector control deployments in history.
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