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Gates Co-Leads a Seed Round for Computational Drug-Discovery Startup Nimbus
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In 2011, Bill Gates co-led the seed financing of Nimbus Therapeutics (originally Nimbus Discovery), a biotech built around using computer modeling to design new medicines — partnering closely with Schrödinger, another Gates-backed firm. Nimbus pioneered an unusual structure that spun out drug programs as separate subsidiaries; one of them was later sold to Takeda for billions. The investment fit Gates's recurring thesis that computation could make the slow, costly hunt for new drugs faster and smarter.
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2026
Gates Foundation Trust Sells Off the Last of Its Microsoft Stock
In the first quarter of 2026, the Bill & Melinda Gates Foundation Trust sold its remaining Microsoft shares, fully exiting a position in the very company that created Gates's fortune — capping a long, deliberate diversification away from the stock. The endowment that funds Gates's philanthropy, managed separately from its grant-making through Cascade, is now anchored instead by Berkshire Hathaway, Waste Management, railroads, and heavy-equipment makers. The sale underscored how thoroughly Gates's giving had decoupled from Microsoft's day-to-day fortunes.
2026
Gates's Charitable Endowment Is Now Led by Berkshire, Not Microsoft
By 2026, the publicly disclosed stock portfolio of the Bill & Melinda Gates Foundation Trust — the endowment that funds Gates's philanthropy — was led not by Microsoft but by Berkshire Hathaway, Waste Management, Canadian National Railway, Caterpillar, and Deere. Decades of diversification, plus Warren Buffett's stock gifts, left it concentrated in railroads, waste, heavy equipment, and Buffett's conglomerate, while Microsoft — the source of the original fortune — had largely been sold down. The unglamorous, value-oriented mix reflects the long stewardship of Gates's money manager, Michael Larson, through Cascade Investment.
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